FB2024_02 , released April 23, 2024
Gene Group : INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-A
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General Information
Name
INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-A
Species
D. melanogaster
Symbol
IFT-A
FlyBase ID
FBgg0000075
Date last reviewed
2023-08-08
Number of members
5
Description
Description
Intraflagella Transport (IFT) complex proteins are evolutionary related to coat protein complexes. The IFT-A subcomplex mediates retrograde transport of large proteins/complexes within the intraflagella transport system. It interacts with the BBSome and IFT-B complexes. (Adapted from PMID:22118932, PMID:19575670 and FBrf0223369).
Notes on Group

Orthologs for intraflagellar transport subcomplex-A components TTC21A/B and IFT139 have not been identifed in D.mel (FBrf0223491).

Source Material
The INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-A Gene Group has been compiled using the following publication(s): van Dam and Huynen, 2013.11.6, van Dam et al., 2013, Jékely and Arendt, 2006, and Avidor-Reiss et al., 2004 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
intraciliary retrograde transport
cilium assembly
Cellular Component
non-motile cilium
intraciliary transport particle A
Related Gene Groups
Parent group(s)
INTRAFLAGELLAR TRANSPORT COMPLEXES
Members (5)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
IFT43
Intraflagellar transport 43
(van Dam and Huynen, 2013.11.6, van Dam et al., 2013)
Oseg1
Outer segment 1
IFT122, mecC
(van Dam and Huynen, 2013.11.6, van Dam et al., 2013, Jékely and Arendt, 2006, Avidor-Reiss et al., 2004)
Oseg4
Outer segment 4
IFT121
(van Dam and Huynen, 2013.11.6, van Dam et al., 2013, Jékely and Arendt, 2006, Avidor-Reiss et al., 2004)
Oseg6
Outer segment 6
(van Dam and Huynen, 2013.11.6, van Dam et al., 2013, Jékely and Arendt, 2006, Avidor-Reiss et al., 2004)
rempA
reduced mechanoreceptor potential A
IFT140, oseg3, remp
(van Dam and Huynen, 2013.11.6, van Dam et al., 2013, Jékely and Arendt, 2006, Avidor-Reiss et al., 2004)
External Data
Synonyms and Secondary IDs
Synonym(s)
IFT-A
INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-A
Intraflagellar transport particle A
Intraflagellar transport complex A
Intraciliary transport particle A
IFT A
Secondary FlyBase ID(s)
References (5)