Gene Group: UNCLASSIFIED RING DOMAIN UBIQUITIN LIGASES

General Information

Name

UNCLASSIFIED RING DOMAIN UBIQUITIN LIGASES

Species

D. melanogaster

Symbol

E3-RING-U

FlyBase ID

FBgg0000128

Date last reviewed

2019-11-05

Number of members

Description

This group comprises RING domain ubiquitin ligases that do not classify under other groups in FlyBase.

Notes on Group

Du et al., 2011 (FBrf0225318) identified E3 RING domain-encoding genes based on InterPro domain (IPR001841) and Ying et al., 2011 (FBrf0215242) produced a computational survey of RING finger domains. Only genes that have supporting evidence for E3 activity based on direct experiment or phylogenetic/orthology-based prediction are included in the OTHER RING DOMAIN UBIQUITIN LIGASES gene group.

Source Material

The UNCLASSIFIED RING DOMAIN UBIQUITIN LIGASES Gene Group has been compiled using the following publication(s): Zavortink et al., 2020, Ji et al., 2014, Du et al., 2011, Ying et al., 2011, and Eisenhaber et al., 2007 .

Key Gene Ontology (GO) terms

Molecular Function

ubiquitin protein ligase activity

Biological Process

protein ubiquitination

Cellular Component

Related Gene Groups

Parent group(s)

RING DOMAIN E3 UBIQUITIN LIGASES

Members (98)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Bre1

l(3)01640, dBre1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Cbl

Cbl proto-oncogene

D-cbl, dCbl, D-cblL, D-cblS, Dv-cbl

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG1317

(FlyBase, 2017-, Ying et al., 2011)

CG2617

38E.2

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG2681

EG:100G10.2

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG2991

(FlyBase, 2017-, Ying et al., 2011)

CG4080

(FlyBase, 2017-, Ying et al., 2011)

CG4325

EG:22E5.12

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG5334

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG5347

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG5555

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG6923

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG7376

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG7694

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG8141

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG9014

BG:DS08249.3

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG10761

(FlyBase, 2017-, Ying et al., 2011)

CG10916

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG11360

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG11414

ZNF598

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG12099

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG12477

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG13344

anon-EST:GressD1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG13442

(FlyBase, 2017-, Ying et al., 2011)

CG13481

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG13605

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG14983

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG15141

(FlyBase, 2017-)

CG15814

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG16781

(FlyBase, 2017-, Ying et al., 2011)

CG17019

dRNF34

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG17329

BG:DS02740.5, DS02740.5

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG17717

(FlyBase, 2017-, Ying et al., 2011)

CG17721

(FlyBase, 2017-)

CG17991

(FlyBase, 2017-, Ying et al., 2011)

CG31807

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG32369

(FlyBase, 2017-)

CG32847

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG33552

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG34308

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

CG34375

(FlyBase, 2017-)

Cnot4

CCR4-NOT transcription complex subunit 4

NOT4, dNOT4

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

detr

detour

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

dgrn

degringolade

STUbL

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

dnr1

defense repressor 1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

dor

deep orange

Vps18, EG:171E4.1, Dof, l(1)7

(FlyBase, 2017-)

deltex

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

elfless

(FlyBase, 2017-)

elgi

early girl

Nrdp1, dNrdp1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Fancl

(FlyBase, 2017-)

Hakai

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

hiw

highwire

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Iru

Iruka

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Kaz

Katazuke

(Zavortink et al., 2020, FlyBase, 2017-)

Kpc1

Kip1 ubiquitination-promoting complex subunit 1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

lmgA

lemming A

lmg, lemming, l(2)03424, APC11

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Ltn1

Listerin E3 ubiquitin protein ligase 1

l(3)76BDr

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

March5

(FlyBase, 2017-, Ying et al., 2011)

mdlc

midlife crisis

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

mib1

mind bomb 1

D-mib, l(3)72CDa, Dmib, mib, Mindbomb

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

mib2

mind bomb 2

l(2)37Be, Be, D-mibl

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Mkrn1

Makorin 1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Mrgn1

Mahogunin ring finger 1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

msl-2

male-specific lethal 2

MSL2, MSL, kmA

(FlyBase, 2017-, Du et al., 2011)

Mul1

Mitochondrial E3 ubiquitin protein ligase 1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

mura

murashka

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

mus302

mutagen-sensitive 302

mus(3)302

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

neur

neuralized

neu, Neuralised

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

nopo

no poles

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Nse1

Non-SMC element 1

(FlyBase, 2017-, Ying et al., 2011)

Pex2

Peroxin 2

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Pex10

Peroxin 10

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Pex12

Peroxin 12

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Pits

Protein interacting with Ttk69 and Sin3A

(FlyBase, 2017-)

Pli

Pellino

(FlyBase, 2017-, Ji et al., 2014)

POSH

Plenty of SH3s

DPOSH, l(2)k15815

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Rchy1

Ring finger and CHY zinc finger domain containing 1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Rnf11

Ring finger protein 11

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Rnf146

Ring finger protein 146

Iduna

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

RNF220

ring finger protein 220

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

roq

roquin

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Sce

Sex combs extra

dRING, dRING1, Ring, Sex comb extra, RING1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

sina

seven in absentia

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

sinah

sina homologue

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

sip3

septin interacting protein 3

Hrd1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

snama

something that sticks like glue

l(2)rQ313, BcDNA:LD21643, mini-me, mnm

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

snky

sneaky

ms(3)ry4, ms(3)snky, ms(3)4, ms(3)sneaky

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

sordd1

suppression of retinal degeneration disease 1 upon overexpression 1

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

sordd2

suppression of retinal degeneration disease 1 upon overexpression 2

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Sou

Souji

(Zavortink et al., 2020, FlyBase, 2017-)

stc

shuttle craft

l(2)35Cb, l(2)br33, br33, BG:DS04929.4

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

tey

teyrha-meyrha

(FlyBase, 2017-)

Topors

Topoisomerase I-interacting protein

dTopors, nuclear blebber, nbl

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Traf6

TNF-receptor-associated factor 6

dTRAF2, Traf2, dTraf6, EP325

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Trc8

TRC8 ring finger protein

DTrc8

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Ubr1

Ubr1 ubiquitin ligase

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Ubr3

Ubr3 ubiquitin ligase

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

Vps11

Vacuolar protein sorting 11

(FlyBase, 2017-, Du et al., 2011, Ying et al., 2011)

External Data

Equivalent Group(s)

Other resource(s)

Synonyms and Secondary IDs

Synonym(s)

RING-containing domain ubiquitin-ligases

RING proteins

Really Interesting New Gene finger domain

E3 ligase

Ubiquitin ligase

RING-E3

RING

RING FINGER DOMAIN PROTEINS

E3-RING-O

UNCLASSIFIED RING DOMAIN UBIQUITIN LIGASES

OTHER RING DOMAIN UBIQUITIN LIGASES

E3-RING-U

Secondary FlyBase ID(s)

References (7)

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