FB2024_01 , released February 22, 2024
Gene Group : AGC-KINASES
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General Information
Name
AGC-KINASES
Species
D. melanogaster
Symbol
AGC
FlyBase ID
FBgg0000231
Date last reviewed
2015-03-25
Number of members
30
Description
Description
The AGC kinase subfamily are serine/threonine kinases that were originally defined based on the sequence similarity of the catalytic domain found in PKA, PKG and PKC enzymes, from which the subfamily derives its name. AGC kinases, in general, prefer substrates containing basic residues. (Adapted from FBrf0132098 and PMID:20027184).
Notes on Group
Source Material
The AGC-KINASES Gene Group has been compiled using the following publication(s): Sopko et al., 2014, Manning et al., 2002, Shieh et al., 2002, and Morrison et al., 2000 .
Key Gene Ontology (GO) terms
Biological Process
Cellular Component
Enzymatic activity
Enzyme name (EC)
non-specific serine/threonine protein kinase (2.7.11.1)
Related Gene Groups
Parent group(s)
Members (30)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Protein kinase, cAMP-dependent, catalytic subunit 1
PKA, DC0, DCO, PKAc, protein kinase A
Protein kinase, cAMP-dependent, catalytic subunit 2
PKA, DC1, PKA C2
Protein kinase, cAMP-dependent, catalytic subunit 3
PKA, DC2, 5-23, cAMP-dependent protein kinase 3
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
atypical protein kinase C
DaPKC, atypical PKC, l(2)k06403, aPKCζ, PKC
inactivation no afterpotential C
PKC, eye-PKC, protein kinase C, dPKC53E(ey), PKCi
Protein C kinase 53E
PKC, protein kinase C, dPKC, dPKC53E(br), Pkc1
Protein C kinase 98E
PKC, dPKC98F, PKC 98F, Pkc3, protein kinase C
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
foraging
dg2, PKG, l(2)06860, FOR/PKG
Protein kinase, cGMP-dependent at 21D
DG1, PKG
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Akt kinase
Akt1, dAkt, PKB, Dakt1, dPKB
genghis khan
l(2)09373, Genghis Kahn, dMRCK
G protein-coupled receptor kinase 1
rhodopsin kinase, Gprk-1, RK
G protein-coupled receptor kinase 2
nosh
JIL-1 kinase
JIL1, Su(var)3-1, Su-var(3)1, Suppressor of variegation 3-1, MSK
Phosphoinositide-dependent kinase 1
Pk61C, dPDK1, Dstpk61, Protein kinase 61C, PDK
Protein kinase N
l(2)06736, Protein kinase related to protein kinase N, l(2)45Ca, 3-2, Dpkn
Rho kinase
Drok, ROCK, Rho-associated kinase, DRho-kinase, DRhk
Ribosomal protein S6 kinase
dS6K, S6 kinase, p70S6K, fs(3)07084, RPS6-p70-protein kinase
Ribosomal protein S6 kinase II
RSK, ign, ignorant, p90 ribosomal S6 kinase, rsk2
S6 Kinase Like
Bin4, Pk17E, Protein kinase-like 17E, 3-10
sticky
Citron, citron kinase, dck, l(3)7m-62, cit
warts
lats, Warts/Lats, large tumor suppressor, LATS1, Lats/Warts
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
AGC
AGC-KINASES
AGC serine/threonine kinases
Secondary FlyBase ID(s)
References (5)