Dual Specificity Phosphatases (DSP) can dephosphorylate both tyrosine and serine/threonine residues. Additionally, DSPs may target a much larger and diverse set of substrates, including phosphoinositide lipids, RNA 5'-triphosphate and carbohydrates. (Adapted from FBrf0227974).
Notes on Group
CG3632, mtm, Mtmr6, Pten and PTPMT1 are also members of the PHOSPHATIDYLINOSITOL PHOSPHATE AND INOSITOL PHOSPHATE PHOSPHATASES gene group.
CG14411, CG5026 and Sbf are predicted to encode pseudophosphatases in FBrf0227974 and are therefore omitted from this group.