FB2024_01 , released February 22, 2024
Gene Group : SPLICEOSOME COMPLEX A
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General Information
Name
SPLICEOSOME COMPLEX A
Species
D. melanogaster
Symbol
SPL-C-A
FlyBase ID
FBgg0000535
Date last reviewed
2016-09-05
Number of members
50
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex A, the pre-spliceosome, is composed of U1 and U2 snRNPs and proteins involved in recognition of the 5' splice site and branch point. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group
Source Material
The SPLICEOSOME COMPLEX A Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Cellular Component
Related Gene Groups
Members (50)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
DEAH-box helicase 15
half pint
pUf68, pUbsf, DPUF68, PUF60, poly U binding factor 68kD
Heterogeneous nuclear ribonucleoprotein at 87F
hrp36, P11, hnRNPA1, Hrb87Fa, Q16
Heterogeneous nuclear ribonucleoprotein at 98DE
hrp38
noisette
SF3A3, l(3)j3E7
PHD finger protein 5a
pre-mRNA processing factor 5
pre-mRNA processing factor 40
SR-related CTD associated factor 6
BP1047, BP1040
Splicing factor 3a subunit 1
Splicing factor 3a subunit 2
Splicing factor 3b subunit 1
Splicing factor 3b subunit 2
Splicing factor 3b subunit 3
Splicing factor 3b subunit 5
Splicing factor 3b subunit 6
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
Small ribonucleoprotein particle protein SmD1
snRNP69D
Small ribonucleoprotein particle protein SmD2
snRNP2
Small ribonucleoprotein particle protein SmD3
guf, gut feeling, l(2)90/37
Small ribonucleoprotein particle protein SmE
snRNPE
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
sans fille
fs(1)1621, fs(1)A1621, liz, splicing necessary factor, SNF/D25
small nuclear RNA U1 at 21D
U1, U1 snRNA, snRNA:U1, U1snRNA, U1-21.1
small nuclear RNA U1 at 82Eb
U1, U1 snRNA, U1:82Eb, U1-82.3, U1snRNA
small nuclear RNA U1 at 95C a
U1, U1 snRNA, U1:95Ca, DMU1951, U1snRNA
small nuclear RNA U1 at 95C b
U1, U1 snRNA, U1snRNA, U1:95Cb, snRNA:U1
small nuclear RNA U1 at 95C c
U1, U1 snRNA, U1snRNA, snRNA:U1, U1:95Cc
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, snRNA:U2, U2-14B
small nuclear RNA U2 at 34AB a
U2, U2 snRNA, dU2, U2-131A, U2:34ABa
small nuclear RNA U2 at 34AB b
U2, U2 snRNA, dU2, U2-131B, U2:34ABb
small nuclear RNA U2 at 34AB c
U2, U2 snRNA, dU2, snRNA:U2
small nuclear RNA U2 at 38AB a
U2, U2 snRNA, dU2, U2-141A, snRNA:U2
small nuclear RNA U2 at 38AB b
U2, U2 snRNA, dU2, U2:38ABb, U2-141B
small ribonucleoprotein particle U1 subunit 70K
U1-70K, snRNP70K, U1 snRNP, Dm70K, 70K
small ribonucleoprotein particle U1 subunit C
snRNP-U1, U1C, snRNPC
Small nuclear ribonucleoprotein G
SmG, snRNPG
Spliceosomal protein on the X
squid
hrp40, l(3)j4B4, RRM3, l(3)EP3631, hnRNP A
U2A
U2A', l(2)43Ee, dU2A'
U2 small nuclear riboprotein auxiliary factor 38
U2AF, dU2AF38, dU2AF38
U2 small nuclear riboprotein auxiliary factor 50
U2AF, dU2AF50, l(1)9-21, dU2AF50, l(1)14Cc
External Data
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPL-C-A
SPLICEOSOME COMPLEX A
Intron definition complex
Pre-spliceosome
Complex A
Secondary FlyBase ID(s)
References (4)