FB2024_02 , released April 23, 2024
Gene Group : SPLICEOSOME COMPLEX C
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General Information
Name
SPLICEOSOME COMPLEX C
Species
D. melanogaster
Symbol
SPL-C-C
FlyBase ID
FBgg0000536
Date last reviewed
2016-09-05
Number of members
91
Description
Description
Nuclear pre-mRNA splicing is catalyzed by the spliceosome which assembles in a step-wise manner. Complex B undergoes a number of structural rearrangements and U4 and U1 snRNPs dissociate to generate complex C, the catalytic spliceosome. (Adapted from PMID:24452469 and PMID:23118483).
Notes on Group

Complex B goes through transition intermediates Bact and B* prior to forming complex C (PMID:24452469 and PMID:23118483). These have not been curated as gene groups.

Source Material
The SPLICEOSOME COMPLEX C Gene Group has been compiled using the following publication(s): Lu and Matera, 2014, Cvitkovic and Jurica, 2013, and Saluz et al., 1988 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
mRNA splicing, via spliceosome
Cellular Component
U2-type catalytic step 2 spliceosome
Related Gene Groups
Parent group(s)
SPLICEOSOME COMPLEX INTERMEDIATES
Members (91)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
abs
abstrakt
abstract
(Cvitkovic and Jurica, 2013)
BCAS2
BCAS2
dBCAS2
(Cvitkovic and Jurica, 2013)
Bin1
Bicoid interacting protein 1
dSAP18, SAP18
(Cvitkovic and Jurica, 2013)
Brr2
Brr2 U5 snRNP complex subunit
l(3)72Ab
(Cvitkovic and Jurica, 2013)
Bx42
Bx42
Skip
(Cvitkovic and Jurica, 2013)
c12.1
c12.1
(Cvitkovic and Jurica, 2013)
cactin
cactin
(Cvitkovic and Jurica, 2013)
Cdc2rk
Cdc2-related kinase
Dcdrk
(Cvitkovic and Jurica, 2013)
Cdc5
Cell division cycle 5
cdc5-like
(Cvitkovic and Jurica, 2013)
CG3225
(Cvitkovic and Jurica, 2013)
CG3436
(Cvitkovic and Jurica, 2013)
CG3511
(Cvitkovic and Jurica, 2013)
CG4849
eEF2
(Cvitkovic and Jurica, 2013)
CG4935
BG:DS02740.2
(Cvitkovic and Jurica, 2013)
CG5808
BcDNA:GH01073
(Cvitkovic and Jurica, 2013)
CG5986
BEST:LP03871
(Cvitkovic and Jurica, 2013)
CG6015
(Cvitkovic and Jurica, 2013)
CG6179
(Cvitkovic and Jurica, 2013)
CG7483
eIF4AIII, eIF4A3, l(3)84Fi, eIF4A-III, eIF4A
(Cvitkovic and Jurica, 2013)
CG7974
(Cvitkovic and Jurica, 2013)
CG8833
(Cvitkovic and Jurica, 2013)
CG9667
(Cvitkovic and Jurica, 2013)
CG10324
(Cvitkovic and Jurica, 2013)
CG10466
(Cvitkovic and Jurica, 2013)
CG10907
(Cvitkovic and Jurica, 2013)
CG11777
(Cvitkovic and Jurica, 2013)
CG11839
(Cvitkovic and Jurica, 2013)
CG11964
(Cvitkovic and Jurica, 2013)
CG12259
(Cvitkovic and Jurica, 2013)
CG12343
(Cvitkovic and Jurica, 2013)
CG12818
(Cvitkovic and Jurica, 2013)
CG13625
(Cvitkovic and Jurica, 2013)
CG14641
(Cvitkovic and Jurica, 2013)
CG15432
(Cvitkovic and Jurica, 2013)
CG15525
(Cvitkovic and Jurica, 2013)
CG16865
BG:DS00941.3
(Cvitkovic and Jurica, 2013)
CG16890
BG:DS00797.4
(Cvitkovic and Jurica, 2013)
CG17168
(Cvitkovic and Jurica, 2013)
crn
crooked neck
yok, EG:30B8.1, l(1)2, yolky, l30
(Cvitkovic and Jurica, 2013)
cyp33
cyclophilin-33
(Cvitkovic and Jurica, 2013)
Cypl
Cyclophilin-like
(Cvitkovic and Jurica, 2013)
Es2
Es2
(Cvitkovic and Jurica, 2013)
fand
fandango
fas, XAB2
(Cvitkovic and Jurica, 2013)
Hsc70-1
Heat shock protein 70 cognate 1
Hsc70, Heat shock protein cognate 1, Hsc1
(Cvitkovic and Jurica, 2013)
l(1)10Bb
lethal (1) 10Bb
l(1)G0169
(Cvitkovic and Jurica, 2013)
l(2)37Cb
lethal (2) 37Cb
l(2)E104, Cb
(Cvitkovic and Jurica, 2013)
mago
mago nashi
mgn, l(2)57Ca
(Cvitkovic and Jurica, 2013)
mdlc
midlife crisis
(Cvitkovic and Jurica, 2013)
ncm
nucampholin
(Cvitkovic and Jurica, 2013)
noi
noisette
SF3A3, l(3)j3E7
(Cvitkovic and Jurica, 2013)
pea
peanuts
(Cvitkovic and Jurica, 2013)
Phf5a
PHD finger protein 5a
(Cvitkovic and Jurica, 2013)
Prp8
pre-mRNA processing factor 8
(Cvitkovic and Jurica, 2013)
Prp18
Prp18
(Cvitkovic and Jurica, 2013)
Prp19
Pre-RNA processing factor 19
l(2)07838, Gbp
(Cvitkovic and Jurica, 2013)
salsa
salsa
(Cvitkovic and Jurica, 2013)
Sf3a1
Splicing factor 3a subunit 1
(Cvitkovic and Jurica, 2013)
Sf3a2
Splicing factor 3a subunit 2
(Cvitkovic and Jurica, 2013)
Sf3b1
Splicing factor 3b subunit 1
(Cvitkovic and Jurica, 2013)
Sf3b2
Splicing factor 3b subunit 2
(Cvitkovic and Jurica, 2013)
Sf3b3
Splicing factor 3b subunit 3
(Cvitkovic and Jurica, 2013)
Sf3b5
Splicing factor 3b subunit 5
(Cvitkovic and Jurica, 2013)
Sf3b6
Splicing factor 3b subunit 6
(Cvitkovic and Jurica, 2013)
Slu7
Slu7
(Cvitkovic and Jurica, 2013)
SmB
Small ribonucleoprotein particle protein SmB
Sm B, Small ribonucleoprotein particle protein B
(Cvitkovic and Jurica, 2013)
SmD1
Small ribonucleoprotein particle protein SmD1
snRNP69D
(Cvitkovic and Jurica, 2013)
SmD2
Small ribonucleoprotein particle protein SmD2
snRNP2
(Cvitkovic and Jurica, 2013)
SmD3
Small ribonucleoprotein particle protein SmD3
guf, l(2)90/37, gut feeling
(Cvitkovic and Jurica, 2013)
SmE
Small ribonucleoprotein particle protein SmE
snRNPE
(Cvitkovic and Jurica, 2013)
SmF
Small ribonucleoprotein particle protein SmF
DebB, Deb-B
(Cvitkovic and Jurica, 2013)
snRNA:U2:14B
small nuclear RNA U2 at 14B
U2, U2 snRNA, dU2, snRNA:U2, U2:14B
(Lu and Matera, 2014)
snRNA:U2:34ABa
small nuclear RNA U2 at 34AB a
U2, U2 snRNA, dU2, snRNA:U2, U2:34ABa
(Lu and Matera, 2014)
snRNA:U2:34ABb
small nuclear RNA U2 at 34AB b
U2, U2 snRNA, dU2, U2:34ABb, snRNA:U2
(Lu and Matera, 2014)
snRNA:U2:34ABc
small nuclear RNA U2 at 34AB c
U2, U2 snRNA, dU2, snRNA:U2
(Lu and Matera, 2014)
snRNA:U2:38ABa
small nuclear RNA U2 at 38AB a
U2, U2 snRNA, dU2, snRNA:U2, U2-141A
(Cvitkovic and Jurica, 2013)
snRNA:U2:38ABb
small nuclear RNA U2 at 38AB b
U2, U2 snRNA, dU2, U2:38ABb, U2-141B
(Lu and Matera, 2014)
snRNA:U5:14B
small nuclear RNA U5 at 14B
U5, U5 snRNA, snRNA:U5, U5:14B, dU5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:23D
small nuclear RNA U5 at 23D
U5, U5 snRNA, U5:23D, snRNA:U5, dU5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:34A
small nuclear RNA U5 at 34A
U5, U5:34A, U5 snRNA, dU5, snRNA:U5
(Lu and Matera, 2014, Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U5:35D
small nuclear RNA U5 at 35D
U5, U5 snRNA, dU5, U5:35D
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U5:38ABa
small nuclear RNA U5 at 38AB a
U5, U5 snRNA, U5:38ABa, dU5, snRNA:U5
(Lu and Matera, 2014)
snRNA:U5:38ABb
small nuclear RNA U5 at 38AB b
U5, U5 snRNA, dU5, snRNA:U5, U5:38ABb
(Lu and Matera, 2014)
snRNA:U5:63BC
small nuclear RNA U5 at 63BC
U5, U5:63BC, U5 snRNA, snRNA:U5, dU5
(Lu and Matera, 2014, Saluz et al., 1988)
snRNA:U6:96Aa
small nuclear RNA U6 at 96A a
U6, U6-1, U6 snRNA, snRNA-b, snRNA:U6
(Saluz et al., 1988)
snRNA:U6:96Ab
small nuclear RNA U6 at 96A b
U6, U6-2, U6:96Ab, U6 RNA, U6 snRNA
(Cvitkovic and Jurica, 2013, Saluz et al., 1988)
snRNA:U6:96Ac
small nuclear RNA U6 at 96A c
U6, U6 snRNA, U6 RNA, U6:96Ac, U6-3
(Saluz et al., 1988)
SNRPG
Small nuclear ribonucleoprotein G
SmG, snRNPG
(Cvitkovic and Jurica, 2013)
Spx
Spliceosomal protein on the X
(Cvitkovic and Jurica, 2013)
Tango4
Transport and Golgi organization 4
(Cvitkovic and Jurica, 2013)
tsu
tsunagi
Y14, Y14/Tsunagi
(Cvitkovic and Jurica, 2013)
U2A
U2A
U2A', l(2)43Ee, dU2A'
(Cvitkovic and Jurica, 2013)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SPLICEOSOME COMPLEX C
SPL-C-C
SLP-C-C
Secondary FlyBase ID(s)
References (4)